Volume 1 · Attributed research edition · Microbes and cancer

Fusobacterium nucleatum promotes tumor progression in KRAS p.G12D-mutant colorectal cancer by binding to DHX15

Huiyuan Zhu; Man Li; Dexi Bi; Huiqiong Yang; Yaohui Gao; Feifei Song; Jiayi Zheng; Ruting Xie; Youhua Zhang; Hu Liu; Xuebing Yan; Cheng Kong; Yefei Zhu; Qian Xu; Qing Wei; Huanlong Qin

Nature Communications · 2024-02-24 · Experimental and translational research

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Nature Publishing Group · Version of record, publisher-supplied full-text XML archived in Europe PMC; correction notices linked where present.

DOI: 10.1038/s41467-024-45572-w

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Mouse, cell and tissue evidence depends on specific tumor genetics and microbial context. Proposed microbiota manipulation is not an established human treatment and cannot replace oncology care. A mechanism in KRAS p.G12D models should not be generalized to all colorectal tumors.

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No retraction or correction notice found in the checked sources. Publisher-supplied full-text XML (article title/type and related notices), Europe PMC core publication types, and publisher-deposited Crossref update-to/updated-by/relation metadata checked on 2026-10-22. Bounded record checks are not a comprehensive guarantee of article integrity; Crossref and repository metadata may be incomplete or lag publisher updates.

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