Volume 1 · Attributed research edition · Microbes and cancer

Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells

Felix Schöpf; Gian L Marongiu; Klaudia Milaj; Thiemo Sprink; Judith Kikhney; Annette Moter; Daniel Roderer

Nature Communications · 2025-08-29 · Structural and molecular research

Explore the evidence

Ask about this article. Its paper agent retrieves exact passages with links back to their context.

Original sourceNature Communications

Nature Publishing Group · Version of record, publisher-supplied full-text XML archived in Europe PMC; correction notices linked where present.

DOI: 10.1038/s41467-025-63451-w

Full original text →

License & editionCC BY 4.0

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

License evidence

Interpretation limits

Structural biology, recombinant expression and binding experiments identify molecular interactions rather than clinical treatment benefits. Binding affinity is not evidence of a safe or effective drug, vaccine, screening test or preventive dental intervention in humans.

Publication status check

No retraction or correction notice found in the checked sources. Publisher-supplied full-text XML (article title/type and related notices), Europe PMC core publication types, and publisher-deposited Crossref update-to/updated-by/relation metadata checked on 2026-10-22. Bounded record checks are not a comprehensive guarantee of article integrity; Crossref and repository metadata may be incomplete or lag publisher updates.

Verification date: 2026-10-22

Edition changes

Narrative text with normalized layout; original references retained. Figures, tables, displayed equations and separately licensed third-party material are omitted. Consult the original for definitive pagination and visual evidence.

Preservation record

Text SHA-256: 6f701482b10a88f4c74b49d67b21eeb6fb46ee90deb4d9608960f5bdcbe8dec8

15,312 words in this edition.