Volume 1 · Attributed research edition · Microbiome and prevention

Nitrate as a potential prebiotic for the oral microbiome

B. T. Rosier; E. Buetas; E. M. Moya-Gonzalvez; A. Artacho; Alex Mira

Scientific Reports · 2020-07-30 · In vitro biofilm experiment

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Nature Publishing Group · Version of record, publisher-supplied full-text XML archived in Europe PMC; correction notices linked where present.

DOI: 10.1038/s41598-020-69931-x

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Biofilms from 12 healthy donors grown in vitro are not a clinical prevention trial. Changes in pH, lactate and relative abundance do not demonstrate fewer cavities, less periodontitis or systemic benefits in patients. Nitrate is a candidate for investigation, not a validated replacement for oral hygiene or professional care.

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Verification date: 2026-10-22

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